Which population is primarily targeted for the human papillomavirus (HPV) vaccine?

The primary target population for the human papillomavirus (HPV) vaccine is preteens aged 11 to 12 years. This age group is recommended for vaccination because the immune response to the vaccine is stronger when given before the onset of sexual activity, which typically begins during adolescence. Vaccines are most effective when administered prior to potential exposure to the virus, as this helps to prevent the development of HPV-related cancers and conditions later in life.

Vaccination during this age range also allows for catch-up vaccinations in older adolescents who may not have received the vaccine in early adolescence. The recommendation is based on public health strategies to decrease the prevalence of HPV and its associated health risks, underscoring the importance of vaccination during early preteen years to achieve optimal community immunity.