Which of the following vaccines needs to be refrigerated?

Shingrix requires refrigeration to maintain its effectiveness and stability. This vaccine, which protects against shingles (herpes zoster), should be stored at 2°C to 8°C (36°F to 46°F), which is typical for many vaccines that are sensitive to temperature fluctuations. Proper refrigeration is essential to ensure that the vaccine remains potent and safe for administration.

Understanding storage requirements is crucial for maintaining the integrity of vaccines, as improper storage can lead to reduced efficacy or even complete failure of the vaccine to confer immunity. This is particularly important in a practice setting where vaccines are handled and administered regularly.