What type of vaccine typically requires multiple doses to achieve immunity?

What type of vaccine typically requires multiple doses to achieve immunity?

• A. Live attenuated vaccines
• B. Inactivated vaccines
• C. Toxoid vaccines
• D. Recombinant vaccines

Answer: (B)

Inactivated vaccines typically require multiple doses to achieve immunity because they consist of pathogens that have been killed or inactivated, rendering them unable to replicate or cause disease. To ensure that the immune response is robust and long-lasting, a series of doses are administered. These vaccines often require a primary series followed by boosters to help maintain immunity over time, as they may not stimulate a strong enough response after just one dose. For instance, vaccines against hepatitis B and polio, which are inactivated, are given in a multi-dose schedule to build sufficient immunity levels in the body. The need for a multi-dose regimen reflects the fact that the inactivated virus or bacteria can sometimes elicit a weaker immune response compared to live attenuated vaccines that replicate in the body and often only require a single dose or fewer doses for effective immunity.

Inactivated vaccines typically require multiple doses to achieve immunity because they consist of pathogens that have been killed or inactivated, rendering them unable to replicate or cause disease. To ensure that the immune response is robust and long-lasting, a series of doses are administered. These vaccines often require a primary series followed by boosters to help maintain immunity over time, as they may not stimulate a strong enough response after just one dose.

For instance, vaccines against hepatitis B and polio, which are inactivated, are given in a multi-dose schedule to build sufficient immunity levels in the body. The need for a multi-dose regimen reflects the fact that the inactivated virus or bacteria can sometimes elicit a weaker immune response compared to live attenuated vaccines that replicate in the body and often only require a single dose or fewer doses for effective immunity.